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Can I have Ovarian Hyperstimulation Syndrome in a frozen embryo cycle?

By Juan José Espinós Gómez M.D., Ph.D. (gynecologist).
Last Update: 03/26/2020

No, it's not possible. Embryo cryotransfer is performed in an asynchronous cycle not stimulated with gonadotropins. It can be done with natural cycle in women with very regular periods or with cycles substituted with female hormones.

In case of a substituted cycle, the treatment consists of the administration of an estrogen in the first phase and the association of an estrogen and progesterone in the second phase. Both substances prepare the endometrium for implantation, but have no effect on follicular growth or ovulation. In fact, during a substituted cycle the ovary is slowed down by the effect of the hormones.

 Juan José  Espinós Gómez
Juan José Espinós Gómez
M.D., Ph.D.
Gynecologist
Dr. Juan José Espinós Gómez has a degree in Medicine from the Central University of Barcelona - Reus - and has been awarded the Outstanding Graduate Award.
Licence number: 080823651
Gynecologist. Dr. Juan José Espinós Gómez has a degree in Medicine from the Central University of Barcelona - Reus - and has been awarded the Outstanding Graduate Award. Licence number: 080823651.