Those women who are going to undergo IVF treatment with oocyte donation should undergo several tests, regardless of age. Each of them is listed below:
- CBC with blood count, biochemistry and coagulation.
- blood group + Rh and indirect coombs.
- Thyroid study with TSH, T4L and if possible anti-TPO and anti-TG antibodies.
- Vitamin D.
- Serology for Syphilis, Hepatitis B and C, HIV, Rubella, Toxoplasma and Cytomegalovirus.
- Cytology of the last year if possible (at least negative of the last 3 years if same sexual partner).
For women over 40 years of age, we also recommend having a mammogram within the last year.
For women over 45 years of age, we will extend the study a little more in order to assess that the state of health is suitable for pregnancy:
- Compulsory mammogram.
- Oral glucose 75 overload to detect possible pre-diabetes and better control the increased risk of gestational diabetes at this age.
- Cardiological study with assessment by cardiologist of ECG, blood pressure and cardio echo if possible.
All recipients will undergo an ultrasound to verify that the uterus is normal and that there are no malformations or endometrial problems. In addition, we can offer the possibility of testing the donor for recessive mutations in order to select her and perform genetic matching with her partner or with the sperm donor.
As in other types of assisted reproduction treatments, if the recipient has already undergone several unsuccessful treatments and a possible implantation failure is suspected or if there are previous repeated miscarriages, a more extensive study with the following tests may be considered:
- Extensive coagulation study with thrombotic profile.
- Tests at the level of the uterus: 3D Echo or hysteroscopy to check morphology.
- Endometrial tests. A biopsy of the endometrial cells can be used to study if there are chronic infections, if the microbiome is adequate, or if the endometrial receptivity is correct at the time of transfer.
- An immunological study can be considered in case the patient requires any complementary therapy that can improve success rates in complex cases.
