Genetic diseases of autosomal recessive inheritance develop when the child inherits two copies of the gene causing the disease in both parents, who can be sick or carriers of the disease if they have just one copy affected.
The probability of transmitting an autosomal recessive disease to offspring if both parents are carriers is 25%, since the child has to inherit both alleles altered to manifest the pathology. On the other hand, the chances for the child to be a carrier are 50%, though.
Read the full article on: What Are Monogenic Disorders? – Classification & Most Common Types ( 70).
By Marta Barranquero Gómez B.Sc., M.Sc. (embryologist), Zaira Salvador B.Sc., M.Sc. (embryologist) and Sandra Fernández B.A., M.A. (fertility counselor).
Last Update: 11/12/2018
