Semen density and liquefaction

Semen usually has a jelly-like appearance because it needs to have this consistency in order to reach the bottom of the vagina in greater numbers. For this reason, there are proteins called semenogelins that are produced by the seminal vesicle.

However, it is necessary for the semen to undergo a liquefaction process by which it becomes more liquid. In this process, the PSA protein fragments the semenogelins, which will allow the sperm to move up the female reproductive tract in search of the oocyte.